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Its active metabolite, fenofibric acid (FA), prevents apoptosis of retinal endothelial cells and maintains the blood-retinal barrier by preventing tight junction disorganization and hyperpermeability in diabetic conditions

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(10) R Noordam, D A Gunn, C C Tomlin, A B Maier, et al (2013) Serum insulin-like growth factor 1 and facial ageing: high levels associate with reduced skin wrinkling in a cross-sectional study British Journal of Dermatology, 2013 Mar, Volume 168 (Issue 3), Pages 533-8