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But we can say at this point that heart benefits are not directly correlated to weight loss, and there is enough molecular data to warrant actual experiments in the heart to begin to understand what the drug does. Researchers trigger sex reversal with one DNA mutation Insertion of one tiny mutation outside a gene caused mice to develop as males instead of females, researchers found

[2] Gastrointestinal adverse effects were predominantly related to nausea, vomiting, diarrhoea, and constipationsymptoms consistent with the known pharmacological effects of GLP-1 receptor agonists on gastric motility

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(B) The enhancement of AMP/ATP ratio stimulates AMPK activity