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The model predicts that initial knock-down of Keap1 by siKEAP1 is counteracted by increasing Nrf2 concentrations, which subsequently upregulate Keap1 and Srxn1 mRNA production (Fig 3C)

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Diabetes, heart failure and beyond: elucidating the cardioprotective mechanisms of sodium glucose cotransporter 2 (SGLT2) inhibitors

D-Ribose , a naturally occurring simple sugar, serves as the fundamental structural backbone for cellular energy