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(2023) 20:e202200872

When saliva flow decreases, food and drinks do not dissolve properly, leaving flavours muted, distorted or metallic

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We also look to the future of this field and comment on how the concept of multi-receptor agonists will continue to progress for the treatment of metabolic disease

2) Acid-sensitive cleavable linkers: Mylotarg, Besponsa, Trodelvy The acid-sensitive strategy is to use a lower pH of the endosome (pH = 5-6) and lysosome (pH = 4.8) compartments compared to the cytoplasm (pH = 7.4) to trigger the hydrolysis of an acid-labile group within the linker, such as a hydrazone

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