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Quick Answer: Significant weight loss alone, regardless of mechanism, can restore ovulation and menstruation in women with obesity-related anovulation In obesity, this extra estrogen contributes to anovulation, irregular cycles, and increased endometrial growth
Long interested in Holst's work, in 1990 Novo Nordisk recruited his colleague Schwartz to develop small molecules able to activate the GLP receptor in the pancreas (Molteni, Chen)
If you feel anxious or depressed, and your doctor prescribes an antidepressant, don't worry about potential weight gain
In the case of GLP-1s, this can mean semaglutide or tirzepatide made in a compounding pharmacy rather than dispensed as an FDA-approved brand-name product
As the body begins to unload some of the energy it has on board, and you begin to slip below your Personal Fat Threshold, your pancreas may regain function, and you may be less dependent on medications
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