Broadly, patients are claiming to have developed non-arteritic anterior ischemic optic neuropathy (NAION), which coincided with taking semaglutide, the active ingredient in Ozempic and Wegovy, the two most popular brands of the drug
As indicated in the learning curves for logistic regression (Fig
However, at therapeutic doses, the net effect of the racemic mix is predominantly that of a cardiac beta 1 stimulant, with little change in peripheral resistance (Westfall et al, 2018)
GLP-1 agonists affect fetal weight, growth and skeletal ossification in animal studies, although liraglutide and exenatide do not cross the placenta
Kirkman HN, Hendrickson EM
it is a synthetic version of exendin-4, a peptide found in the venom of the Gila monster