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Metabolism The metabolism of TPM involves hydroxylation, hydrolysis, and glucuronidation

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In consideration of the dual roles of GLP-1RAs in hypoglycemic effects and preventing CVD among T2DM patients, we reviewed the cardiovascular effects and molecular mechanisms of GLP-1RAs in CVOTs, animal models and cultured cells, and discuss how these findings transform pharmacotherapies for T2DM, and even expand the indication of this important category of anti-diabetic drugs to CVD patients without diabetes

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But keep in mind that nausea can also be a symptom of pancreatitis (inflammation in your pancreas)

1 RELATED: Paleo-Friendly Foods That Support GLP-1 Activity While these drugs were initially developed to treat type 2 diabetes, they are now also prescribed for people with metabolic dysfyunction 2 or obesity, 3 and some people are turning to them for general weight loss