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5-Amino-1MQ has shown to inhibit NNMT, preventing Nicotinamide from entering the NAD+ Salvage Pathway and converting into NAD+

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Because nicotinamide would otherwise re-enter the NAD+ salvage pathway through NAMPT and NMN, NNMT activity sits at a junction between cellular methylation capacity and NAD+ regeneration, which is why the enzyme became a target after Kraus and colleagues (Nature, 2014) reported the consequences of antisense Nnmt knockdown in white adipose tissue and liver

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And they have no known pharmacological interactions

Mechanism: AOD 9604 stimulates lipolysis and inhibits lipogenesis in fat cells via beta-3 adrenergic receptors