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Stavsky, J

Oral glutathione is hydrolysed by intestinal peptidases before systemic absorption, yielding minimal increases in hepatic GSH levels

However, the mechanism of action of glutamine in the immune cells of cancer patients remains unclear, and further research is needed on the inhibitors of glutamine metabolism and their mechanisms of action, as well as the potential broader application of combined immune checkpoint inhibitors

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Uric acid conversely induces lipid accumulation and insulin resistance (IR), thereby forming a vicious cycle of uric acid and insulin [74]