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doi: 10.3390/biom11040557 82 PiazeraBKLGomesDVVigrioPSalernoVPVaismanM

Industry publications echo this: PharmaFocus Europe declares that Digital Twins in Pharma are revolutionizing drug development, bioprocessing, and personalized medicine by enabling dynamic optimization and regulatory-ready modeling ( [30] )

The program included weekly follow ups and very gradual dose increases, which helped keep side effects minimal and made the process feel safe and well monitored

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However, translating animal doses to human equivalents remains imprecise, and the conservative approach favors starting at lower doses and increasing only if needed

J Pharm Biomed Anal 5(162):272285 Satapathy SK, Al-Mahtab M, Singh SP, Akbar SMF, Ala A, Schiano TD (2024) Hepatology: An Evidence-Based Clinical Compendium