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Alterations in the gut microbiome may influence the expression and activity of the sodium/iodine symporter (NIS), a protein essential for iodine transport into thyroid follicular cells (Nicola et al., 2009)

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Since only limited body weight reductions have been previously reported following SGLT2i treatment, hyperphagia is reportedly one of the causes of this limited weight loss

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5) Leclerc D, Sibani S, Rozen R

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