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doi: 10.1038/s41467-019-10210-3 73 Melwani DaswaniM.VanceS

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Overall, these data suggest that TNF- treatment induces trophoblast mitochondrial respiratory dysfunction, a phenotype that can be rescued by NR treatment

References McCoy, A

However, there is still a significant difference between the WL that can be achieved with bariatric surgery and the currently approved obesity pharmacotherapies and there is heterogeneity in treatment responses with GLP-1 RA (for example people with T2D may achieve less WL compared to those without diabetes in clinical trials, despite similar lifestyle interventions) [13, 14]