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Due to interference with production of vitamin K-dependent clotting factors, use of more than 400 IU of vitamin E daily with warfarin might increase prothrombin time (PT), INR, and the risk of bleeding,

Here is where the safety picture gets complicated

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A healthcare provider can determine if switching is appropriate based on individual goals and tolerance

3) Add an additional 4ml of sterile saline solution (provided) into the amber nasal spray bottle and tighten the white nasal atomizer

Track progress to keep yourself motivated