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At higher supplemental doses (500 to 3000 mg daily), niacinamide can cause nausea, liver enzyme elevation, or glucose intolerance, but these effects are unlikely at the low doses used in compounded formulations

Diabetes Care 2020

American Journal of Clinical Nutrition, 101 (6), 1320S1329S

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For example, analysis of four studies on suicidality in adults with bipolar disorder, major or bipolar depressive disorder or no mental illness found that liraglutide was not linked to significantly increased rates of suicidal ideation (having thoughts of suicide).Two further studies of exenatide in patients with alcohol use disorder and liraglutide in bipolar disorder found no significant difference in suicidal behaviour compared with placebo