This suggests GLP-1 drugs may act earlier in the addiction cycle, reducing cue reactivity and craving, rather than reducing reward after use
A patient should always be given lifestyle recommendations when starting a GLP-1, as this will optimize the results when taking the medication, says Holly Lofton, MD, director of NYU Langones Medical Weight Management Program in New York City
GLP-1-induced AMPK and LXR-mediated ABCA1 expression are involved in GLP-1 protective effects
Although how exactly these drugs help in weight loss is not known, as GLP-1 agonists slow the movement of food traveling from the stomach to the small intestine, it makes people feel full quicker and for longer, and so, it is thought to boost weight loss because people tend to eat less as result of the medication
doi: 10.3390/nu17132145 92
Biological function of L-carnitine L-carnitine works together with carnitine palmitoyl transferase (CPT) and carnitine-acylcarnitine translocase (CACT) on the mitochondrial membrane to form an efficient transport system (8)
