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Hanke S, Mann M

Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent

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This results in: Higher ATP production more energy available for both high-intensity bursts and sustained training sessions

For example, if their chronic migraine is 100% one sided, I may give additional on that side of the head, taken from the opposite side where they have no or minimal pain

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