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The drugmaker said earlier this week that its CT-388 weight loss injection was entering a phase III trial the final stage before a company can seek regulatory approval marking the latest development in Roche's nascent but fast-growing pipeline of treatments for obesity and related conditions

It dissolves well in DMSO at 1mg/ml However, adding water may cause cloudiness In that case, applying ultrasonic treatment for 2 seconds usually clears the solution Consequently , proper handling ensures accurate experimental results and consistent performance

The scale of the GLP-1 market reflects how effective these drugs are for significant weight loss, typically 15% to 25% of body weight over 12 to 18 months in clinical trials

New dual agonists (GIP/GLP-1) are showing profound impact not only on weight loss and glycemic control but also on cardiovascular outcomes