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Diets that contribute to excessive SUA levels can induce the formation and deposition of MSU crystals, and other factor changes, such as diet-induced fluid acidification and salt deposition, also promote the growth of urate crystallization [24]

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Its promise lies in its durability, but it currently faces significant technical hurdles regarding the accuracy of delivery, long-term safety, and the complexity of in vivo editing [139]

doi: 10.1615/jlongtermeffmedimplants.v16.i1.90 69 HegdeV.UthappaU

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