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Glucagon suppression: Amylin inhibits glucagon secretion Reduces hepatic glucose production Better glucose control Indirect weight loss benefit Particularly helpful for diabetes 5

100% achieved 5% or more, 93% achieved 10% or more, and 83% achieved 15% or more in Phase 2

Telomerase is the enzyme responsible for maintaining and extending telomeres, the protective caps at the ends of chromosomes that shorten with each cell division

doi: 10.1371/journal.pone.0001944 44 KhanNSDasI

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It may be associated with hypertension, bradyarrhythmia and macula oedema in patients with increased risk, such as those with diabetes mellitus