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Because GLP-1 activates brain regions involved in appetite and mood, some patients initially experience mood changes or vivid dreams

These effects are typically dose-dependent and reversible upon discontinuation

Beyond the irregular periods and potential fertility challenges, PCOS often brings an uphill battle with weight gain that can feel overwhelming and unfair

Symptoms worth watching for We recommend paying attention to the following symptoms, as they likely suggest your levothyroxine levels may need to change: A racing heart, anxiety, tremor, sweating, or trouble sleeping, which can mean your levels are too high, either from the absorption change or from weight loss reducing how much levothyroxine you need Returning fatigue, feeling colder, constipation, or low mood, which can mean your levels have dropped None of these is an emergency on their own, but theyre worth mentioning to your GP

Because these surgeries bypass the part of the gut where absorption happens, the American Society for Metabolic and Bariatric Surgery notes that lifelong injections are often required