Figure S23
The decline of BBB and BCB are involved in many neurological diseases (Blanchette and Daneman, 2015), including, e.g., Alzheimers (Erickson and Banks, 2013
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Bioactive compounds such as Withaferin A and Withanone trigger the production of reactive oxygen species (ROS) and activate the tumor suppressor p53 [207, 209,210,211]
392 However, impaired mitochondrial function in astrocytes reduces their capacity to metabolize fatty acids, leading to neurotoxicity from fatty acids, which could further exacerbate the pathological process of PD
Cho ma przeszkody, zanim dotrze do pacjentw, jest ju wstrznity konkurencyjnym krajobrazem i pokaza, jak daleko mog posun si terapie oparte na inkretynach, szczeglnie w otyoci