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Because of their glucose lowering effects, therapies that enhance incretin actions through inhibiting degradation of endogenous incretins or through activation of the GLP-1 receptor are now in use for the treatment of type 2 diabetes ( ATP channels and in postprandial hypoglycemia after gastrointestinal surgery, where the delivery of nutrients to the small intestine is altered resulting in both hyperglycemia and an exaggerated secretion of GLP-1

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Cell 132 , 2742

There is a long history of medical interventions designed to help people control their weight, none of which have halted the rise in obesity

Mediators Inflamm 2:3336 Savica V, Santoro D, Mazzaglia G, Ciolino F, Monardo P, Calvani M, Bellinghieri G, Kopple JD (2005) l-Carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients