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Thus, our data show that Phe and its major metabolites accumulated in PKU provoke extensive DNA damage in glial cells probably by ROS formation and that L-car may potentially represent an adjuvant therapeutic agent in PKU treatment

[DOI] [PubMed] [Google Scholar] 3.Fielding R.A., Vellas B., Evans W.J., Bhasin S., Morley J.E., Newman A.B., van Kan G.A., Andrieu S., Bauer J., Breuille D., et al

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