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There is no absolute contraindication, and the combination is commonly prescribed in UK clinical practice for patients with both cardiovascular conditions and type 2 diabetes, though individualised medical assessment is essential

"The exact mechanism of how GLP-1 analogues reduce alcohol intake is still being investigated but it is thought to involve curbing cravings for alcohol that arise in subcortical areas of the brain that are not under conscious control," writes Professor Carel le Roux, of University College Dublin, leading the study

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doi: 10.2337/diabetes.51.8.2642 165 FintiniDInzaghiEColajacomoMBocchiniSGrugniGBrufaniCet al