It is essential for maintaining hepatic glucose balance and alleviating insulin resistance in MASLD
I absolutely have to do exercise just like I have to brush my teeth. Rhonda Patrick She works out about 5 to 6 hours a week total broken down like this: Two sessions a week that are CrossFit style, one hour each, first 30 minutes is heavy strength training, last 30 minutes is HIIT (rowing machine, assault bike, lighter cleans with more reps) Two more sessions a week with her girlfriends, about an hour and 20 each, same style but more social and more recovery time between sets Running about 4 to 6 miles a week total, sometimes with her husband, which she genuinely enjoys Weekend hikes with the family, sometimes with a sprint up a hill, but mostly just moving in nature Even just 10 minutes of vigorous exercise immediately increases neuronal connections in the brain The data for this is insane 9 minutes a day of vigorous bursts (3 minutes, 3 times) links to a 40% reduction in all-cause mortality, 40% reduction in cancer mortality, and 50% reduction in cardiovascular mortality The biggest unexpected benefit of heavy strength training was not physical I would say the biggest effect was on my brain and the ability to handle stress better
Blood tests may be used to rule out nutritional deficiencies
While the IH-dependent pro-oxidant state appears to negatively regulate both critical periods, cell-autonomous HIF1a signaling during the first critical period of adult neurogenesis appears to orchestrate adaptations that enhance the neuronal generation following termination of IH
As always, these therapies are not one-size-fits-allbut the science suggests they may have a place in personalized, preventative care for GLP therapies represent a fascinating evolution in modern medicine
Brandt, N., Gunnarsson, T
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