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Description

This approach provides additional time savings and confidence in the data trends across biochemical assays since the cells used were all plated, exposed and processed at the same time

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Ocular ointments are generally preservative-free, provide good long-term lubrication and can provide sustained drug delivery [30] , which is useful for reducing the frequency of administration, particularly during sleeping hours

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But there are several obstacles to the development of this senolytic approach such as the long-term effect of CAR-T cells therapy with possible aspecific toxicity in different organs 56 , the cost and the difficulty during process development 57 or the selection of non-exhausted T cells to generate efficient therapy 58,59

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