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Data analysis was carried out using PeakView software (AB Sciex, version 1.2.0.3) as described previously 20 , and the average values obtained from duplicated measurements were adopted as the results for each HDAC assay

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After 48 h, the cells were treated with 0.2 mM sCSD 1 h prior to treatment with 200 ng ml 1 of IL-22

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