Important contraindications and cautions include: Active peptic ulceration or history of gastrointestinal bleeding Haemophilia or other bleeding disorders Hypersensitivity to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) Children under 16 years (risk of Reye's syndrome) Third trimester of pregnancy Severe hepatic impairment According to the Summary of Product Characteristics (SmPC) and NHS advice, aspirin should be taken with or after food to minimise gastric irritation
This is much higher and faster than other weight loss medications
As of 2025, retatrutide remains under clinical investigation and has not received approval from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA) for routine clinical use in the UK
Semaglutide Semaglutide is a medication used for weight loss and blood sugar management that mimics a natural hormone to regulate appetite, helping individuals achieve sustainable weight loss and improved metabolic health
Patients with ulcerative colitis and Crohns disease saw possible anti-inflammatory benefits from the medication
This is a more holistic approach than injecting synthetic hormones, as it works within your bodys existing feedback loops