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CEO Lars Fruergaard Jrgensen on Thursday acknowledged the sharp share price reaction after two consecutive late-stage trials showed underwhelming weight reduction versus the company's own targets, but said he nevertheless remained "encouraged" by the drug's weight loss profile

FITC-labeled anti-laminB1 antibody was used for marking the nuclear membrane

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Nucleotide exchange factors Fes1 and HspBP1 mimic substrate to release misfolded proteins from Hsp70

Integrated gut microbiota data enabled a random forest (RF) model to distinguish SLE, rheumatoid arthritis, and healthy controls with an area under the curve (AUC) of 0.792

In the real world, it generally involves using doses lower than the established therapeutic amount needed to achieve the intended medical benefit