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Nausea And Reflux Support: Portion Size, Meal Timing, And Trigger Reduction For GLP-1 nausea and reflux, the basics are unglamorous but effective: Smaller portions, more often Avoid very high-fat meals, especially earlier in therapy or after dose increases Don't lie down right after eating Identify your personal triggers (for many people: greasy foods, alcohol, carbonated drinks, very spicy meals) If reflux is prominent, be cautious with peppermint-heavy supplements, since peppermint can relax the lower esophageal sphincter in some people and worsen symptoms

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