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In regular situations, the HPA axis monitors and modulates immune regulation through numerous hormones, such as glucocorticoids [14-18]
Lipedema causes symmetrical, disproportionate fat accumulation primarily in the legs and arms, predominantly affecting women
The reported incidence of lactic acidosis in patients receiving metformin hydrochloride is very low (approximately 0.03 cases/1000 patient-years, with approximately 0.015 fatal cases/1000 patient-years)
The DNA sequence of the D23A mutant was verified by DNA sequencing
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