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Individuals considering use should weigh the strong preclinical cognitive enhancement evidence against the complete absence of controlled human safety data and the theoretical oncogenic concerns
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Perineural injection of medications for BPI is an emerging technique, and its efficacy remains to be validated
Rat studies have noted embryofetal mortality, structural abnormalities, and alterations to growth at maternal exposures below the maximum recommended human dose (MRHD) based on exposure AUC
Evaluation of the retinas of albino mice and of monkeys did not reveal evidence of retinal degeneration
Gallbladder-related events, a risk with rapid weight loss across all obesity medications, occurred in a small percentage of participants and were associated with very rapid early weight loss without adequate dietary fat intake
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