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Aussagen zu spezifischen Wirkmechanismen werden aus rechtlichen Grnden nicht getroffen

This restriction exists because freezing causes ice crystal formation within the solution

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In typical PINK1-Parkin-mediated mitophagy, damaged mitochondria encapsulated in autophagosomes depend on key membrane fusion factors, including Rab7, small GTPase-driven homotypic fusion, and the HOPS (homotypic fusion and vacuole protein sorting) complex, for docking and fusion with lysosomes [136, 137]

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