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High oral bioavailability Caco-2 cell assays showed excellent passive and active membrane transport with no detectable efflux (Neelakantan et al., 2018)

B is crucial for the metabolism of fats, drugs, and steroids and for the activation of other vitamins (it helps convert vitamin B to its active form and aids the conversion of tryptophan to niacin)

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Nevertheless, supplementation should ideally be guided by clinical assessment and, where appropriate, blood testing to confirm deficiency before commencing long-term high-dose therapy

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Importantly, AOD-9604 does not bind to growth hormone receptors, which is why it lacks the glucose-elevating and IGF-1-stimulating effects of full-length growth hormone