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Under 3.5% chloral hydrate anaesthesia, mice were administrated with 5 mg/kg BLM or with 100 l PBS by intratracheal instillation

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After mice were orally administrated curcumin (100 mg/kg), plasma concentrations reached 2.25 g/ml (6.1 M) 32 , whereas the levels of curcumin in the intestine was remarkably high (177.04 g/g) 32