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Im Gegensatz zu Wegovy (Semaglutid, nur GLP-1) und Mounjaro (Tirzepatid, GLP-1 + GIP) kann Retatrutid zustzlich die Glukagon-Rezeptoren aktivieren

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GerhartHines Z, Dominy JE Jr, Blattler SM, et al The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+)

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Clinical research further reinforces the beneficial effects of GLP-1RAs on DPN