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Beyond its vascular effects, Pycnogenol is a formidable, broad-spectrum antioxidant

doi: 10.1038/s41590-021-00993-3 119 GaoXSongYWuJLuSMinXLiuLet al

Indeed, it was demonstrated that heterodimerization of 1-cysPrx with GSH-saturated GSTP results in S -glutathionylation of the oxidized cysteine in 1-cysPrx followed by subsequent spontaneous reduction of the mixed disulfide and restoration of enzymatic activity (Manevich et al., 2004)

not intended as therapeutic claims

The overall cost of treatment depends on the number of sessions required, which typically ranges from 10 to 30 injections for visible skin whitening

and the Jiangsu Provincial Key Research Development Program (grant number BE2016794)