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The insulin-per-kilogram proxy is a clean, useful gauge, but it is a proxy for a clamp it cannot reproduce, and it is blind to residual C-peptide unless you account for it

( Addenda B and D1 are available via the internet on the CMS website

doi: 10.1136/gutjnl-2012-304353 75 DickerD

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In people with type 2 diabetes mellitus (T2DM), this secretion is impaired, thus disrupting normal homeostasis and resulting in increases in blood glucose level[3]