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Together, these aspects warrant caution in the chronic use of GLP-1 receptor agonists during periods of active growth and maturation, reinforcing the need for long-term, sex-stratified studies to ensure safe and effective therapeutic application

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Zu et al., indeed, demonstrated in Drosophila melanogaster that the deletion of miR-14 increased the levels of triacylglycerol and diacylglycerol while its overexpression resulted in the converse effect 94