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Patients with T2DM treated with denosumab exhibit lower glycated hemoglobin levels compared with those treated with bisphosphonates or calcium and vitamin D supplementation, highlighting the role of the RANK-RANKL system and implicating DPP-4 as a potential mediator between bone remodeling and energy metabolism [3]

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Victoza is FDA-approved for type 2 diabetes (2010) at maximum 1.8 mg/day