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In summary, regulating mitophagy can significantly inhibit adipocyte apoptosis, reduce lipogenesis, and promote the browning of white adipose tissue to alleviate over-obesity but most recent studies have focused on the mitophagy and obesity-associated co-morbidities, and relatively few studies have investigated the specific mechanisms of the protective role in obesity

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Results from three phase 1 trials of NNC9204-1177, a glucagon/GLP-1 receptor co-agonist: effects on weight loss and safety in adults with overweight or obesity

Physiological Effects: Released endogenous hGH then exerts its effects on target tissues, promoting growth, protein synthesis, and metabolic processes