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Effect of pentoxifylline on proteinuria, markers of tubular injury and oxidative stress in non-diabetic patients with chronic kidney disease - placebo controlled, randomized, cross-over study

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(5) In the management of diabetes (including newly diagnosed type 2 diabetes), insulin therapy should be initiated as early as possible if there is significant unexplained weight loss[1]

SCFAs produced by probiotic bacteria contribute to immune regulation by inhibiting inflammatory pathways, enhancing the production of anti-inflammatory cytokines, and maintaining intestinal barrier integrity

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Reference Ribeiro et al