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Once c-Met receptors are occupied, excess ligand gets cleared without contributing to synaptogenesis

It describes these symptoms typically emerging within days of a new or increased dose and persisting for one to two weeks before improving, often manageable with dietary adjustment and hydration

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Male patients often experience hypogonadism and low testosterone levels, while female patients frequently present with polycystic ovary syndrome, characterised by hyperandrogenism and menstrual irregularities [16]