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This is perhaps a little surprising, since IGF-1 is a growth promoting substance, hence we would expect that it could promote growth for every type of cancer
However, confocal microscopy revealed these capsid foci partially co-localised with the envelope gB viral protein and required the NEC, suggesting they were either very closely apposed to the nuclear membrane or had already reached the perinuclear space, the latter of which was ultimately confirmed by electron microscopy