In a note ahead of the findings, BMO Capital Markets analyst Evan Seigerman said his base-case assumption was for the drug to show weight loss of around 20% to 23%, with at least a 50% reduction in knee pain
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Despite this, people with type 2 diabetes tend to lose less weight on a GLP-1 than people who don't have the condition, and for reasons that aren't quite clear, says Silvana Obici, MD, chief of the division of endocrinology at Stony Brook Medicine and medical director of the Stony Brook University Hospital Diabetes Center in New York
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GMP (Good Manufacturing Practice) is an FDA-mandated certification