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The LC-MS data included some missing values, which were handled as follows: if the missing values accounted for more than 20% of samples, the metabolite was excluded from the analysis

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These medications work by mimicking the action of naturally occurring GLP-1, a hormone released by the intestine in response to food intake

Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach

Conclusion and Future Perspectives Current research shows that MO exerts its multiple immune-related effects primarily through directly eliminating pathogens or modulating the balance of pro- and anti-inflammatory mediators released from various kinds of immune cells by regulating the activity of signaling pathways, such as the canonical NF-B pathway (Figure 1)