cycling on and off glp-1 REPEATED USE MAY PROMOTE LONG TERM WEIGHT GAIN: A new mice study found exactly that. Repeated cycles of GLP-1's may have long term adverse effects the very thing they were A Guide to Outdoor Fitness

L-Glutathione is one of many antioxidants thats naturally present in the human body

For example, exendin-4 at the concentration of 50 nM downregulated the expression of NF-B p65 in isolated human pancreatic cells [62]

This shift manifests as bloating, gas, digestive discomfort , and impaired nutrient absorption

doi: 10.1016/j.ympev.2016.12.029 267 StetterM

Study authors also noted the risk reductions were more pronounced in the cohorts with psoriasis than in those with obesity or diabetes without psoriasis, and that findings were consistent across all sensitivity analyses. Study authors concluded that GLP-1 receptor agonists should be considered for patients with psoriasis and comorbid obesity or diabetes.

Bottom Line: Electrolytes Can Help, But Use Them for the Right Reason Electrolyte supplements while using GLP-1 medications can be helpful, especially when your food and fluid intake are low, you are sweating heavily, you are recovering from diarrhea or vomiting, or you feel headachey, weak, lightheaded, or dehydrated