most common side effects of glp 1 Adverse GLP-1 class drugs. Gastrointestinal issues are GLP-1: Genetic Variants Related to

Patients should eat smaller, more frequent meals rather than large portions, avoiding high-fat and heavily spiced foods that may exacerbate nausea

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While the gastrointestinal effects (nausea, diarrhea, vomiting) are similar to other GLP-1 medications like Wegovy and Mounjaro, retatrutide has one unique finding: dysesthesia (abnormal touch sensations) in 20.9% of patients at the 12mg dose in TRIUMPH-4, and 12.5% at 12mg in the larger TRIUMPH-1 trial

In a 26-week study, tirzepatide was studied to determine its effect on biomarkers of nonalcoholic steatohepatitis (NASH) and fibrosis in patients with T2DM