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Opioid use may worsen gastric retention Higher prevalence of recent opioid use in the high RGC group Suggests an additive effect on gastric motility No difference in indication or duration of therapy Whether patients used GLP-1 RAs for diabetes or weight loss did not affect risk Duration of therapy was not a significant predictor Interpretation Withholding 7.5 days higher risk of retained gastric contents Fasting 21.3 hours strongest predictor of high RGC These thresholds optimize sensitivity and specificity for detecting risk

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Timeline Breakdown: Initial Weeks (14): Most common when starting or increasing doses

Beginner GLP-1 tips: Start low and increase slowly Priori So happy we have this option to treat obesity

Even temporary exposure to freezing temperatures (like being left outside or in a car) can make it ineffective