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Vitamin B12 plays a vital role in maintaining healthy nerve cells, supporting red blood cell production, and aiding in DNA synthesis

The Phase 2 obesity trial published in the New England Journal of Medicine reported substantial weight reduction over 48 weeks, while a separate Phase 2 trial in people with type 2 diabetes evaluated glycemic and body-weight effects

REDEFINE 2 (combination, with type 2 diabetes) In adults with type 2 diabetes, the combination achieved 13.7% weight reduction versus 3.4% for placebo

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Homocysteine has been identified as a pathogenic feature of NAFLD in humans and alcoholic fatty liver disease in a rodent model

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